MIAMI VETERINARY SPECIALISTS PARTICIPATES IN LANDMARK STUDY ON NEW TREATMENTS FOR PARAPLEGIC DOGS
Funded by the Morris Foundation for Animals
Posted by NC State University, College of Veterinary Medicine
Referring Veterinarians Are Urged To Refer Qualified Patients
Miami Veterinary Specialists is pleased to announce participation in a large multi-center clinical trial comparing the effects of a new drug, PEG (polyethylene glycol) and MPSS to a saline control in dogs with acute spinal cord injuries that are paraplegic with no deep pain. Here is a description of the trial from the Investigators heading the study at North Carolina State University: “PEG acts by fusing damaged axonal membranes and has been shown to be safe in a phase I clinical trial in dogs. This blinded, prospective clinical trial will compare MPSS, PEG, and saline placebo as adjunctive medical therapies to surgical decompression in dogs with acute intervertebral disc herniations.” MVS will be one of 11 centers around the country participating in this study.
REFERRAL PATIENTS ARE NEEDED for participation in this clinical trial. The drug will be offered free of charge to patients. Note: These drugs do not replace the standard of care and will not change any other aspect of the management for each case.
Follow ups post surgery and re-checks will be free of charge to the patient. Pet owner will still be responsible for surgery and diagnostic fees.
Criteria for inclusion in the clinical trial:
*Dogs between 2 and 10 years old and weighing less than 20kgs
*Patients need to be referred quickly. Dog must have been known to be paraplegic with no deep pain for less than 24 hours
*No high dose steroids administered too close to referral time
Infusion of the drug begins immediately before surgery and lasts 24 hours. This study will NOT lengthen the standard hospital stay for surgeries of this type.
“It’s a fantastic clinical trial,” according to Dr. Marc Wosar, DACVS of Miami Veterinary Specialists. “It’s a very large study involving specialty practices and universities across the country. This new drug shows a lot of promise and I think it will give us good information on how to best treat these animals.”
For more information about the study, visit NC State College of Veterinary Medicine.
If you have any questions at all, please feel free to call our doctors anytime at 305-665-2820.